Pharmaceutical Technology

Drug Delivery Approaches and Nanosystems, Volume 2
Drug Targeting Aspects of Nanotechnology

Editors: Raj K. Keservani, MPharm
Anil K. Sharma, MPharm
Rajesh K. Kesharwani, PhD

Drug Delivery Approaches and Nanosystems, Volume 2

In production
Pub Date: July 2017
Hardback Price: $179.95 US
Hard ISBN: 9781771885843
E-Book ISBN: 9781315225364
Pages: Approx 425p w/Index
Binding Type: hardback
Notes: 13 color and 46 b/w illustrations

Drug Delivery Approaches and Nanosystems, Volume 2: Drug Targeting Aspects of Nanotechnology is a thorough presentation of the state-of-the-art research and developments in drug delivery systems using nanotechnology and its applications. This two-volume set addresses the applications of nanotechnology or nano-sized materials in the medical field and the real-world challenges and complexities of current drug delivery methodologies and techniques.

This volume, Drug Targeting Aspects of Nanotechnology, includes 11 chapters that focus on the targeting facet of drug delivery systems. Targeting is a focused maneuver to achieve the specified goals, including achieving the desired result and reaching the specific location. Targeting has now been successfully achieved for several diseases/disorders; however, its role is noteworthy in cancer treatment where chemotherapy is a main course of approach. Nanotechnology-based products have great potential by virtue of their inherent features.

This edited book provides a detailed application of nanotechnology in drug delivery system in health care. The book discusses general principles of drug targeting, material of construction and technological concerns of nanoparticles, and different drug delivery systems and their preparation.

Taken together, the informative chapters will provide researchers and scientists well as faculty and students with valuable research on the effective use of new approaches in advanced drug delivery nanosystems.

Key features:

  • Explores the role of nanoscience to provide site-specific delivery of active pharmaceutical ingredients
  • Explains the targeting to tumor by variety of nanocarriers
  • Focuses on the potential of dendrimers to be exploited for delivery of genetic substances
  • Investigates the promise exhibited by polysaccharides in drug targeting
  • Looks at the profile and applications of glycans, which offer great potential for their use in drug delivery systems
  • Explains the characteristics of nanofibers relevant to drug delivery applications
  • Describes the clinical aspects of nanotechnology, in particular, of carbon nanotubes and graphene
  • Looks at nanocomposite microparticles for pulmonary drug delivery applications
  • Highlights the role of SLNs as topical drug carriers of antimicotic, anti-inflammatory, antibiotic, and antioxidant molecules

CONTENTS:
Preface

1. Drug Targeting: General Aspects and Relevance to Nanotechnology
Preethi Naik, Megha Marwah, Meenakshi Venkataraman, Gopal Singh Rajawat, and Mangal Nagarsenker

2. Nano-Oncotargets and Innovative Therapies
Yamuna Mohanram and Lakshmi Kiran Chelluri

3. Dendrimer Conjugates as Novel DNA and SiRNA Carriers
Yuya Hayashi, Keiichi Motoyama, Taishi Higashi, Hirofumi Jono, Yukio Ando, and Hidetoshi Arima

4. Precise Preparation of Functional Polysaccharide Nanoparticles by Enzymatic Approach
Jun-ichi Kadokawa

5. Polysaccharide-Drug Nanoconjugates as Targeted Delivery Vehicles
Sabyasachi Maiti

6. Glycan-Based Nanocarries in Drug Delivery
Songul Yasar Yıldız, Merve Erginer, Tuba Demirci, Juergen Hemberger, and Ebru Toksoy Oner

7. Physiological and Clinical Considerations of Drug Delivery Systems Containing Carbon Nanotubes and Graphene
Sami Makharza, Giuseppe Cirillo, Orazio Vittorio, and Silke Hampel

8. Nanofibers: General Aspects and Applications
Raghavendra Ramalingam and Kantha Deivi Arunachalam

9. Nanocomposite Microparticles (nCmP) for Pulmonary Drug Delivery Applications
Zimeng Wang, Elisa A. Torrico-Guzmán, Sweta K. Gupta, and Samantha A. Meenach

10. Solid Lipid Nanoparticles for Topical Drug Delivery
Sonia Trombino and Roberta Cassano

11. Hydrophobized Polymers for Encapsulation of Amphotericin B in Nanoparticles
Yoshiharu Kaneo

Index


About the Authors / Editors:
Editors: Raj K. Keservani, MPharm
Rajiv Gandhi Proudyogiki Vishwavidyalaya, India

Raj K. Keservani, MPharm, has more than seven years of academic (teaching) experience from various institutes of India in pharmaceutical education. He has published 30 peer-reviewed papers in the field of pharmaceutical sciences in national and international journals, fifteen book chapters, two co-authored books, and two edited books. He is also active as a reviewer for several international scientific journals. Mr. Keservani graduated with a pharmacy degree from the Department of Pharmacy from Kumaun University, Nainital (UA), India. He received his Master of Pharmacy (MPharm) (specialization in pharmaceutics) from the School of Pharmaceutical Sciences, Rajiv Gandhi Proudyogiki Vishwavidyalaya, Bhopal, India. His research interests include nutraceutical and functional foods, novel drug delivery systems (NDDS), transdermal drug delivery/ drug delivery, health science, cancer biology, and neurobiology.

Anil K. Sharma, MPharm
Lecturer, Delhi Institute of Pharmaceutical Sciences and Research, University of Delhi, India

Anil K. Sharma, MPharm, is working as a lecturer at the Delhi Institute of Pharmaceutical Sciences and Research, University of Delhi, India. He has more than six years of academic experience in pharmaceutical sciences. He has published 26 peer-reviewed papers in the field of pharmaceutical sciences in national and international journals as well as 12 book chapters. He received a bachelor’s degree in pharmacy from the University of Rajasthan, Jaipur, India, and a Master of Pharmacy degree from the School of Pharmaceutical Sciences, Rajiv Gandhi Proudyogiki Vishwavidyalaya, Bhopal, India, with a specialization in pharmaceutics. His research interests encompass nutraceutical and functional foods, novel drug delivery systems (NDDS), drug delivery, nanotechnology, health science/life science, and biology/cancer biology/neurobiology.

Rajesh K. Kesharwani, PhD
Faculty, National Institute of Technology, Warangal, Telangana, India

Rajesh K. Kesharwani, PhD, has more than seven years of research and two years of teaching experience in various institutes of India, imparting bioinformatics and biotechnology education. He has received several awards, including the NASI-Swarna Jayanti Puruskar-2013 by The National Academy of Sciences of India. He has authored over 32 peer-reviewed articles and ten book chapters. He has been a member of many scientific communities as well as a reviewer for many international journals. Dr. Kesharwani received a BSc in biology from Ewing Christian College, Allahabad, India, an autonomous college of the University of Allahabad; his MSc (Biochemistry) from Awadesh Pratap Singh University, Rewa, Madhya Pradesh, India; and MTech-IT (specialization in Bioinformatics) from the Indian Institute of Information Technology, Allahabad, India. He earned his PhD from the Indian Institute of Information Technology, Allahabad, and received a Ministry of Human Resource Development (India) Fellowship and Senior Research Fellowship from the Indian Council of Medical Research, India. His research fields of interest are medical informatics, protein structure and function prediction, computer-aided drug designing, structural biology, drug delivery, cancer biology, and next-generation sequence analysis.




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