Biomedical Engineering/Nanotechnology

Modern Approaches in Identification and Therapeutic Applications of Secondary Metabolites, Volume 1
Volume 1: Role of Secondary Metabolites in Herbal Medicine

Editors: Alpana Joshi, PhD
Subrata K. Das, PhD
Shiva Sharma, PhD

Modern Approaches in Identification and Therapeutic Applications of Secondary Metabolites, Volume 1

In Production
Pub Date: Forthcoming February 2026
Hardback Price: $200 US | £150 UK
Hard ISBN: 9781779642356
E-Book ISBN: 978-1-77964-236-3
Pages: Est 412 pp w/index
Binding Type: hardbound / ebook
Notes: 12 color and 53 b/w illustrations

Secondary metabolites are indispensable to the therapeutic potential of plants because they are responsible for most of a plant’s medicinal properties. Known for their role in combating illnesses, promoting health, and enhancing well-being, secondary metabolites are a cornerstone for traditional and modern therapeutic practices. This new two-volume work, Modern Approaches in Identification and Therapeutic Applications of Secondary Metabolites, combines traditional insights with cutting-edge research and offers solutions to global health issues, leveraging the bioactive properties of secondary metabolites for use in drug development and as complementary and alternative medicines.

Volume 1: Role of Secondary Metabolites in Herbal Medicine addresses how plant-based proteins and secondary metabolites can be used to treat particular diseases, emphasizing precision medicine. It delves into these compounds’ diverse biological activities and applications, including alkaloids, terpenoids, flavonoids, and phenolics, thoroughly examining these natural compounds and highlighting their pharmacological characteristics and molecular mechanisms.

Covering a selection of secondary metabolites of plants and seaweed, the volume looks at new developments in the capacity of anticancer alkaloids to stop tumor growth and trigger the death of cancer cells, considers the antibacterial properties of natural phenolics, evaluates efficacy of secondary metabolites in treating arthritis and osteoarthritis and reversing bone demineralization, explores the antidiabetic activities of herbal drugs, and helps to integrate traditional knowledge with modern technology by applying innovative methodologies like Quality by Design (QbD) in drug development and precision medicine.

Volume 2: Advancements in Herbal Medicine and Integrated Approaches encompasses a wide range of topics, from applying green nanotechnology in enhancing the efficacy of herbal treatments to incorporating biocomputation techniques that leverage machine learning for improved classification and analysis of medicinal plants, offering advanced scientific methods and traditional herbal knowledge and highlighting the unique opportunities to enhance the efficacy and sustainability of natural therapeutics.

Combining traditional insights with cutting-edge research, these volumes offer solutions to global issues like cardiovascular disease and antibiotic resistance to leverage the bioactive properties of secondary metabolites, providing a valuable resource that celebrates the therapeutic legacy of secondary metabolites and promotes sustainable drug discovery practices.

This book is comprised of selected papers from the International Conference on the Science of Rudraksha, October 27-28, 2023; organized by the Shobhit Institute of Engineering and Technology (Deemed-to-be-University), Meerut, India.


Click here for Modern Approaches in Identification and Therapeutic Applications of Secondary Metabolites, 2-volume set


Click here for Modern Approaches in Identification and Therapeutic Applications of Secondary Metabolites, Volume 2: Advancement in Herbal Medicine and Integrated Approaches

CONTENTS:
Preface

PART I: TRADITIONAL KNOWLEDGE AND HERBAL MEDICINE
1. Therapeutic Significance of Rudraksha (Elaeocarpus ganitrus Roxb): A Comprehensive Review

Shiva Sharma and Manisha Rastogi

2. Cultivation of Glycyrrhiza Species and Their Health Benefits to Humans: A Comprehensive Review
Vani Bhatia, Kuldeep Mishra, and Mohit

3. The Role of Seaweed in the Management of Infectious Disease: A Review
Nidhi Saran, Vinit Kumar Sharma, Deepika Rani, and Bhupendra Chauhan

4. Rudraksha: A Special Tree Blessed with Miraculous Powers of Holistic Well-Being
Sunita Chauhan, Priyankar Rai, and Rahul Mishra

PART II: BIOACTIVE COMPOUNDS AND HERBAL MEDICINE
5. Biological Applications of Rudraksha

Sujeet Kumar, Ujjawal Kumar, Monika Kumari, Shiva Sharma, and Manisha Rastogi

6. Recent Synthetic and Medicinal Perspectives of Biologically Important Flavones
Poonam Talwan, Darsh Gautam, and Ranjit Singh

7. Recent Updates in Anticancer Alkaloids: Molecular Mechanism
Shrishti Sharma, Sundhlesh Yadav, Prashant Pandey, Millind Sagar, Shiva Sharma, and Manisha Rastogi

8. Compilation of Pharmacological and Biological Properties of Elaeocarpus ganitrus (Rudraksha) Bead Extracts
Prashant Kumar Pandey, Milind Sagar, Shiva Sharma, and Manisha Rastogi

9. Applications of Secondary Metabolites in Drug Development and Precision Medicine
Isha Agrawal and Manish Vyas

10. Plant-Based Protein with Therapeutic Benefits
Ujjawal Kumar, Sujeet Kumar, Monika Kumari, Simran Raj, Shiva Sharma, and Manisha Rastogi

11. Natural Phenolics in Developing Resistance Against Bacterial Disease
Km Reeta, Alpana Joshi, and Subrata K. Das

PART III: ETHNOPHARMACOLOGY AND HERBAL MEDICINE
12. Evaluation of Anti-Arthritic Activity of Bark Extract of Soymida febrifuga Against Freund’s Complete Adjuvant Induced Arthritic Rats

Vinit Kumar Sharma, Madan L. Kaushik, and Deepika Rani

13. Demineralization of Weight-Bearing Bones Due to Induced Osteoarthritis and Reversal with Commiphora wightii Gum Resin Extract
Beena Rawat

14. Antidiabetic Activities of Herbal Drugs: Mechanisms and Potential
Kajal Gurow and Kanupriya Chauhan

15. Impact of Rudraksha as a Catalyst in Overcoming Depression
Dipika Sharma, Nikki Sharma, and Sweety Pal

16. Iron Metabolism and Cardiovascular Disease
Shubham Rastogi, Rohit Sharma, Shiva Sharma, and Manisha Rastogi

17. Herbal Medicines and Rudraksha Beads for Neurological Disorders
Vipin Dhiman, Gaurav, Sangeeta, Teena, Shiva Sharma, and Manisha Rastogi

18. Quality-By-Design-Assisted Optimization of Mouth-Dissolving Film for the Co-Delivery of Voriconazole and Beauvericin
Deepika Rani, Azhar Khan, and Ranjit Singh

19. Diabetes Mellitus and Covid-19 Complication: A Review
Avichal Kumar, Poonam Talwan, Gaurav Joshi, Navni Sharma, Divya Dhawal Bhandari, Pooja Kumari, Nishant Gautam, Alka Sharma, and Darsh Gautam

Index


About the Authors / Editors:
Editors: Alpana Joshi, PhD
Shobhit Institute of Engineering & Technology, (Deemed-to-be University), Meerut, India

Alpana Joshi, PhD, is a distinguished researcher and academician, currently serving as an Associate Professor at Shobhit University, Meerut, India. She previously served as a Research Professor in the Department of Agricultural Chemistry at Jeonbuk National University, South Korea, and completed a postdoctoral fellowship at the USDA-ARS-FRRL, Utah State University, USA. Dr. Joshi holds a PhD in Molecular Biology from IIT Kharagpur, India, with over 15 years of research experience specializing in molecular biology and genomics. Her research focuses on the intricate mechanisms regulating genetic information and its expression in living organisms. Her expertise extends to gene identification, DNA barcoding, phylogenetic studies, herbal medicine research, and molecular biology and genomics, employing advanced bioinformatics tools for genomic analysis. She has made substantial contributions to scientific research, with numerous national and international publications and the development of multiple GenBank accessions. Additionally, Dr. Joshi is an active reviewer for several prestigious scientific journals.

Subrata K. Das, PhD
Associate Professor, Shobhit Institute of Engineering & Technology (Deemed to be University), Meerut, India

Subrata K. Das, PhD, is an accomplished academic and researcher in the field of biological sciences, currently serving as an Associate Professor at Shobhit University in Meerut, India. His extensive training and research experience span various biological disciplines, particularly in molecular biology and cell biology, which have laid a strong foundation for his career in academia and translational research. Dr. Das has a robust academic background, having completed his doctoral studies with a focus on biological sciences. Prior to his current position, he worked as a postdoctoral fellow at the Moran Eye Center in Salt Lake City, USA, where he contributed to significant research projects. Following that, he served as a Research Professor at Jeonbuk National University in South Korea and held the role of Senior Scientist at the Patanjali Research Institute in Haridwar, India. His diverse experience across different countries and institutions have enriched his research perspective and methodologies. His current research interests focus on phagocytic dysfunction, the development of phagocytosis assays, and drug screening. He has published numerous articles in high-impact SCOPUS-indexed journals, showcasing his contributions to advancing knowledge in his field.

Shiva Sharma, PhD
Associate Professor, Shobhit Institute of Engineering & Technology (Deemed to be University), Meerut, India

Shiva Sharma, PhD, is a skilled researcher with expertise in materials science, nanotechnology, and drug delivery. She is an Associate Professor at the Shobhit Institute of Engineering & Technology, (Deemed-to-be University), Meerut, India. Her work focuses on designing and engineering biomaterials for biomedical applications, optimizing properties like biocompatibility, mechanical integrity, and degradation kinetics. Dr. Sharma is proficient in nanoparticle synthesis and characterization techniques, including SEM, EIS, PPMS, SQUID, FTIR, and UV, and has a deep understanding of nanoparticle behavior and material interactions. She is working on biosensor fabrication, using nanomaterials and biomolecules for enhanced sensitivity and specificity and assessing biocompatibility with both in vitro and in vivo models. Dr. Sharma is also skilled in computational modeling, leveraging tools like eFTIR, NanoDcal, and MATLAB to analyze material properties and well-versed in regulatory requirements for biomedical devices and materials, ensuring compliance with ISO, FDA, and GLP standards.




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