Pharmaceutical Science & Technology

Macular Degeneration
A Progressive Retinal Disorder

Editors: Bhupendra Prajapati, PhD
Rishabha Malviya, PhD
Himanshu Paliwal, PhD
Sonali Sundram, PhD

Macular Degeneration

In Production
Pub Date: Forthcoming August 2025
Hardback Price: $240 US | £180 UK
Hard ISBN: 9781998511242
Pages: Est. 590pp w/index
Binding Type: Hardback / ebook
Notes: 18 color and 63 b/w illustrations

This new book, Macular Degeneration: A Progressive Retinal Disorder, provides an in-depth look at the various features of age-related macular degeneration (AMD). It provides a complete overview of this common retinal condition by focusing on the experience of ophthalmology and associated fields. The book explores the complex systems that drive AMD causes and pathology, as well as the most recent advances in diagnostic procedures and treatment plans. It also looks at genetic factors, inflammatory pathways, and the possibilities of artificial intelligence. It digs into AMD complexities, investigating its etiology, pathogenesis, diagnostic techniques, and developing therapy strategies.

The book bridges the gap between fundamental research and clinical applications, giving significant insights for ocular health researchers, physicians, educators, and students. It covers topics from molecular pathways to cutting-edge therapeutics, making it an invaluable resource for anybody interested in engaging in the study of AMD and improving patient care. The book goal is to increase understanding of AMD and motivate additional research and collaboration in the prevention, diagnosis, and treatment of this vision-threatening illness.

Providing a detailed compilation in an effort to understand the complexities of age-related macular degeneration, this volume will enlighten and encourage additional investigation, promoting a continual debate and collaboration in the never-ending effort of curing this difficult retinal illness.

CONTENTS:
Preface

1. Age-Related Macular Degeneration: Etiology, Pathophysiology, and Stages

Stephen Chijioke Emencheta, Chioma Miracle Ojiako, Chukwuka Kanayo Oranu, Chukwuemezue Praises Onyekwe, Charles Kenechukwu Enebechi, Ebele Benedette Onuigbo, Anthony Amaechi Attama, and Aman Upaganlawar

2. Risk Factors for Progression of Age-Related Macular Degeneration
Rajnish Kumar Yadav, Alok Shiomurti Tripathi, Bidhyut Kumar Dubey, Jyoti Anurag, Prabhjot Singh, Laiba Rind, Alok Kumar Shukla, and Bhupendra G. Prajapati

3. The Role of Inflammation on Age-Related Macular Degeneration
Johnson O. Oladele, Bankole E. Ofeniforo, and Oluwaseun T. Oladele

4. Genetics of Age-Related Macular Degeneration (AMD): Current Understanding and Clinical Implications
Disha D. Shah, Parv A. Patel, Mehul R. Chorawala, and Bhupendra G. Prajapati

5. Macular Degeneration and Ocular Drug Delivery System: Causes, Symptoms, Diagnosis, and Treatment
Nazneen Siddique, Priyanka Shah, Himanshu Solanki, Brijesh Parlekar, and Bhupendra Prajapati

6. Imaging and Artificial Intelligence in Diagnosis of Macular Degeneration
Ashutosh Agarwal, Bhupendra Prajapati, Chandni Chandarana, and Parixit Prajapati

7. Biomarkers and Medical Laboratory Testing for Age-Related Macular Degeneration
Nkereuwem Sunday Etukudoh, Obiora Reginald Ejinaka, Uchejeso Mark Obeta, and Amaechi Eze Odono

8. Molecular Pathology-Based Therapeutic Interventions of Macular Degeneration: Unravelling Complexity
Alkeshkumar Patel, Archita Patel, Meghana Patel, Manish Nandpal, Manan Raval, Kamal Dua, Sachin Kumar Singh, Bhupendra Prajapati, Gaurav Gupta, Ravish Patel, and Samir Patel

9. Nanotechnology: Revolutionizing the Delivery of Drugs to Treat Macular Degeneration
Deepak Sharma, Devesh U. Kapoor, Bhupendra G. Prajapati, Pinkal H. Patel, and Mansi Gaur

10. Gene Therapies for Age-Related Macular Degeneration
Neelakanta Sarvashiva Kiran, Chandrashekar Yashaswini, and Bhupendra G. Prajapati

11. Anti-VEGF Therapy for Age-Related Macular Degeneration
Kaumudi Joshi, Trisha Shetty, Sanket Gehlot, Srishti Shetty, and Saritha Shetty

12. The Role of Dysregulated miRNAs in the Pathogenesis, Diagnosis, and Treatment of Age-Related Macular Degeneration
Aravindh S., Kanagaraj C., Neelakanta Sarvashiva Kiran, and Bhupendra Prajapati

13. Role of Vitamins and Minerals in Controlling Macular Degeneration
Shivani N. Jani, Hitesh B. Katariya, and Bhupendra G. Prajapati

14. Liposome in Targeting Macular Degeneration
Ravish J. Patel, Nidhi Trivedi, Vidhi Pandya, Amit A. Patel, Samir G. Patel, Archita J. Patel, Bhupendra G. Prajapati, Manan A. Raval, Amit Alexander, and Vijaykumar B. Sutariya

15. Current Insights and Future Prospects in Nanoemulsion-Based Delivery Systems for Macular Degeneration
Arti A. Bagada, Bhupendra Prajapati, Priya V. Patel, and Monika B. Sangani

16. Biomaterial-Based Therapeutic Strategies for Macular Degeneration: An Explicative Review
Dipanjan Karati, Swarupananda Mukherjee, and Bhupendra G. Prajapati

17. Antibody-Based Therapies for Age-Related Macular Degeneration (AMD): Challenges and Opportunities
Mehul R. Chorawala, Disha D. Shah, Bhavarth P. Dave, and Bhupendra G. Prajapati

18. Long-Acting Intraocular Delivery Approaches for Biological Therapy of Age-Related Macular Degeneration
Devesh Kapoor, Mansi Gaur, Sudarshan Singh, and Bhupendra Prajapati

19. Implants and Inserts in Diagnosis and Treatment of Macular Degeneration
Akruti Khodakiya, Sudarshan Singh, Bhupendra Prajapati, Ami Makwana, and Kruti Jadwani

20. Polysaccharide-Based Formulations in Treatment of Macular Disease
Vipul Prajapati, Princy Shrivastav, Sonali Singh, Suraj Kadlag, Pankaj Maheriya, and Bhupendra Prajapati

21. Recent Updates in Synthetic and Biological Molecules for Treatment/Therapy of Macular Degeneration Drugs
Popat Mohite, Abhijeet Puri, Henry O. Det, and Bhupendra Prajapati

22. Artificial Intelligence in Macular Degeneration: Detection and Therapy
Nisarg C. Patel, Sapna M. Rathod, Bhupendra G. Prajapati, and Jigna Prajapati


Index


About the Authors / Editors:
Editors: Bhupendra Prajapati, PhD
Professor, Department of Pharmaceutics, Shree S. K. Patel College of Pharmaceutical Education and Research, Ganpat University, Gujarat, India

Bhupendra Prajapati, PhD, is a Professor in the Department of Pharmaceutics, Shree S. K. Patel College of Pharmaceutical Education and Research, Ganpat University, Gujarat, India. He has more than 20 years of academic and research experience and has published more than 100 research and review papers in international and national journals. He has edited three books and has authored 20 book chapters in the field of novel drug delivery. He has published two Indian patents and has three applications under evaluation. He is a reviewer for three high-impact journals and is on the editorial boards of several scientific journals.

Rishabha Malviya, PhD
Associate Professor, Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University, Greater Noida, Uttar Pradesh, India

Rishabha Malviya, PhD, has 12 years of research experience and is presently working as Associate Professor in the Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University, Greater Noida, Uttar Pradesh, India. His areas of interest include formulation optimization, nanoformulation, targeted drug delivery, localized drug delivery, and characterization of natural polymers as pharmaceutical excipients. He has authored more than 150 research and review papers for national and international journals of repute. He holds over 50 patents and has published many papers in reputed national and international journals, for which he received an outstanding reviewer award from Elsevier. He has edited 13 books (Wiley, Springer Nature, CRC Press/Taylor and Francis, Apple Academic Press, River Publisher, Lambert, and OMICS Publishing Group) and authored 15 book chapters. His name has been included in the World Top 2% Scientists list by Elsevier BV and Stanford University. He is reviewer, editor, and editorial board member for more than 50 national and international journals. He was an invited author for the magazine Atlas of Science as well as a pharma magazine dealing with B2B industry, Ingredient South Asia. He completed his BPharm at Uttar Pradesh Technical University and MPharm (Pharmaceutics) at Gautam Buddha Technical University, Lucknow Uttar, India.

Himanshu Paliwal, PhD
Associate Professor, Department of Pharmaceutics, Sanjivani College of Pharmaceutical Education and Research, India

Himanshu Paliwal, PhD, is currently working as an Associate Professor in the Department of Pharmaceutics, Sanjivani College of Pharmaceutical Education and Research, India. Following his doctoral studies, he worked as a postdoctoral researcher at the Drug Delivery System Excellence Center, Prince of Songkla University, Thailand. His research expertise lies in the development of novel emulsion-based and lipid-based drug delivery systems for pulmonary and eye-related disorders. He has published about 14 research/review articles and 11 book chapters. Additionally, he has also been serving as a referee for various esteemed journals. He completed his PhD from Bhupal Nobles University, India.

Sonali Sundram, PhD
Assistant Professor, School of Medical & Allied Sciences, Galgotias University, Greater Noida, Uttar Pradesh, India

Sonali Sundram, PhD, is Assistant Professor in the School of Medical & Allied Sciences at Galgotias University, Greater Noida, Uttar Pradesh, India. Previously, she worked as a research scientist on a project of ICMR at King George Medical University, Lucknow, India. After that, she joined BBDNIIT (Babu Banarasi Das Northern India Institute of Technology), Lucknow. Her PhD (Pharmacy) work was in neurodegeneration and nanoformulation. Her areas of interest include neurodegeneration, clinical research, and artificial intelligence. She has authored or edited 14 books (Wiley, CRC Press/Taylor and Francis, River Publisher, IOP Publishing) and has organized more than 15 national and international seminars, conferences, and workshops. She has more than eight patents, both national and international, to her credit. She completed both BPharm and MPharm (Pharmacology) at Dr. A.P.J. Abdul Kalam Technical University, Lucknow, India.




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