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Now Available in Paperback The new book is of a contemporary nature that covers significant new knowledge that has emerged during the last two decades and, thus, provides novel antibody phylogenetic perspectives relevant to development of new antibody based therapeutics and vaccines. It fills in the much-needed niche in the area of immunoglobulin genetics across species from a comparative perspective. New insights and perspectives from immunoglobulin genetics from species such as sea lamprey, cattle, marsupial, bat, rat, rabbit, swine etc.—other species other than the traditional subjects of mice and humans, are relevant to antibody design and engineering. These new perspectives find direct application in the cutting-edge areas of antibody design, engineering and therapeutics, antibody-drug conjugates and novel antibody-based vaccines. This book fills the need to provide updated knowledge of this newly exploded area that is finding applications in new drug development. No other competing books on the topic are available in the market. This important book • examines unique structural and functional aspects of antibody genes across species • describes the role of convergent evolution in jawless vertebrates • describes genetic elements that determine antibody diversity and vary across species • reviews mechanisms of antibody diversification across species • describes challenges associated with limited germline immunoglobulin gene diversity • presents mmunogenetic-based research directions toward developing antibody-based drugs for diseases like cancer, autoimmune and viral diseases where conventional therapies fail The book will be of great interest to immunologists, immunology researchers, immunogeneticists, researchers in pharmaceutical & medical science, those involved in the infectious disease and antibody therapeutics areas, and many others. CONTENTS: About the Authors / Editors: Editors: Azad K. Kaushik, DVM, DSc Associate Professor, Department of Molecular and Cellular Biology, University of Guelph, Ontario, Canada Azad K. Kaushik, DSc, is Associate Professor of Immunology at the University of Guelph, Guelph, Ontario, Canada. He has published over eighty articles and book chapters as well as co-edited a book on titled Molecular Immunobiology of Self-Reactivity, a major advance in understanding of the systemic autoimmune diseases in the context of immune function. He is on the editorial boards of several immunology journals and is a consultant to various international organizations, including the US Veterinary Immune Reagent Network and Comparative Immunoglobulin Workshop in USA and IMGT (International ImMunoGeneTics Information System), France. He was recognized as The Esther Z. Greenberg Honors Chair in Biomedical Research, and Visiting Professor, Oklahoma Medical Research Foundation, USA, in 1998. He received BVSc&AH (Honors) in 1976 and MVSc (1978) from the Faculty of Veterinary Science, Hisar, Haryana, India, followed by Docteur es Science in Immunology (1987) from Pasteur Institute (University of Paris VII), Paris, France. Yfke Pasman, MSc University of Guelph, Guelph, Ontario, Canada Yfke Pasman received a BA in veterinary management (1988) and a MSc in Pharmacology (1994) in the Netherlands and worked for several years as a pharmacist. She received MSc in Immunology in 2010 which involved engineering of therapeutic antibodies. Currently, she is a PhD candidate in the laboratory of Dr. Azad Kaushik, working on a project involving bovine antibody genetics and its application in therapeutics and immunodiagnosis. She is a member of American Association of Immunologists and Canadian Society of Immunology. |
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AAP WELCOMES PROF. MOHAMMED KUDDUS, PhD, AS AAP’S NEW ACQUISITIONS EDITOR for books on biotechnology, enzymology, microbiology, bioinformatics, bioremediation, biomedical technology, value-added products etc. Dr. Kuddus is Head of the Department of Biochemistry at the College of Medicine, University of Hail, Kingdom of Saudi Arabia. He is listed in Elsevier/Stanford University World’s Top 2% Scientists. He seeks book proposals from potential editors to consider for publication with Apple Academic Press. Contact: kuddus@appleacademicpress.com for more information. AAP welcomes Dr. Maulin P. Shah as AAP’s new acquisitions editor for books on Applied Microbiology, Environmental Biotechnology and Waste Management. 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Dr. Kulkarni is Adjunct Professor, Faculty of Business, Victorian Institute of Technology, Melbourne, Australia; and Adjunct Professor, Centre of Research Outcome and Impact, Chitkara University, Punjab, India. You can reach him at Email: srkulkarni21@gmail.com for more information. New Book Series: AAP Series on Waste Biomass Valorization will explore the transformation of biomass resources into valuable products, addressing the growing need for sustainable alternatives to fossil fuels and non-renewable resources. For more information and to propose a book, please visit: Click here Congratulations to Hafiz Ansar Rasul Suleria, PhD, for receiving the Dean’s Award for Excellence in Research from the University of Melbourne, Australia, in recognition for his exceptional performance and strong commitment to advanced research in food science. Dr. Suleria is editor of AAP’s book series Innovations in Plant Science for Better Health: From Soil to Fork. 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