Plant Science & Botany

Phytochemistry, Volume 1
Fundamentals, Modern Techniques, and Applications

Editors: Chukwuebuka Egbuna
Jonathan Chinenye Ifemeje, PhD
Stanley Chidi Udedi, PhD
Shashank Kumar, PhD

Phytochemistry, Volume 1

Published. Available now.
Pub Date: December 2018
Hardback Price: See Ordering info
Hard ISBN: 9781771887595
Paperback Price: see ordering info
Paperback ISBN: 978-1-77463-432-5
E-Book ISBN: 9780429426193
Pages: 684pp w/index
Binding Type: hardback / paperback / ebook
Notes: 14 color and 130 b/w illustrations


Reviews
“A comprehensive book on phytochemistry written by professionals from key institutions around the world. . . It provides a framework starting from the introduction, biosynthesis of phytochemicals to their effect on living systems and to the state-of-the-art modern techniques with insights on the discovery of medicinally active compounds through in silico and in vitro studies. . . . . I recommend it to teachers, students, researchers and everyone with interests in phytochemistry.”
— From the Foreword by Timea Polgar, PhD, VP, R&D, Founder, Envision Biotechnology

“Will have a great impact in the field of phytochmistry. It gives a strong background about phytochemicals starting with their different biosynthesis pathways and then discusses to their potential biological activities and using the virtual techniques to find the molecular targets through which the compounds exert their action. This volume is well documented and organized and will be very beneficial to researchers in the phytochemistry field as it also gives a wide overview on the different analytical and chromatographic techniques and their application presented in research.”
—Shahira M. Ezzat, Professor and Head, Faculty of Pharmacy, MSA University, Egypt



NOW AVAILABLE IN PAPERBACK

Phytochemistry, Volume 1: Fundamentals, Modern Techniques, and Applications, the first of this three-volume set provides comprehensive coverage of a wide range to topics in phytochemistry. With chapters from professional specialists from key institutions around the world, the volume starts with an introduction to phytochemistry and details the fundamentals. Part II discusses the state-of-the-art modern methods and techniques in phytochemical research, while Part III provides an informative overview of computational phytochemistry and its applications. Part IV presents novel research findings in the discovery of drugs that will be effective in the treatment of diseases.

The chapters are drawn carefully and integrated sequentially to aid flow, consistency, and continuity. This book will be very useful to researchers, teachers, students, phytochemists, plant biochemists, food and medicinal chemists, nutritionists and toxicologists, chemical ecologists, taxonomists, analytical chemists, industrialists and many others.

Key features:

  • Introduces phytochemistry, its modern history, and the relationship it has with other sciences
  • Discusses the prospects for phytochemists and the future of phytochemical research
  • Explores the biosynthesis of phytochemicals
  • Looks at the biological roles of phytochemicals in animals
  • Discusses phytochemicals as nutraceuticals and pharmafoods
  • Details the role of phytochemistry in plant classification and various phytochemical markers of taxonomic importance
  • Describes the various extraction methods and techniques, including those for used for the isolation and characterization of phytochemicals
  • Provides an overview of the techniques utilized in phytochemotaxonomy.
  • Looks at a variety of techniques used for the isolation and characterization of phytochemicals

Click here for information on Volume 2
Click here for information on Volume 3
See information on the complete set here: Phytochemistry, 3-Volume Set

CONTENTS:
Foreword by Timea Polgar, PhD, VP, R&D, Founder Envision Biotechnology

Preface

PART I: FUNDAMENTALS OF PHYTOCHEMISTRY
1. Introduction to Phytochemistry
Chukwuebuka Egbuna, Jonathan C. Ifemeje, Toskë L. Kryeziu, Minakshi Mukherjee, Hameed Shah, G.M. Narasimha Rao, Laurence John Francis J. Gido, Tijjani Habibu

2. Biosynthesis of Phytochemicals
Tijjani Habibu, Chukwuebuka Egbuna, and Luka D. Carrol

3. Mechanisms of Plant Defense Against Pathogens: Phytoalexins Induction
Hanan M. AL-Yousef and Musarat Amina

4. Biological Roles of Phytochemicals
Onyekere Peculiar Feenna, Nwankwo Chioma Obianuju, Udodeme Helen Ogechukwu, Nnamani Daniel Okwudili, and Ezugwu Christopher Obodike

5. Phytochemicals as Immunomodulators
Behnaz Aslanipour

6. Phytochemicals as Nutraceuticals and Pharmafoods
Anywar Godwin

7. The Role of Phytochemistry in Plant Classification: Phytochemotaxonomy
Felix Ifeanyi Nwafor and Ifeoma Celestina Orabueze

8. Plant Metabolomics
Sagar Satish Datir and Rakesh Mohan Jha

PART II: METHODS AND TECHNIQUES
9. Phytochemical Extraction, Isolation and Detection Techniques
Temitope Temitayo Banjo, Paul Akinniyi Akinduti, Temitope Oluwabunmi Banjo, and Vinesh Kumar

10. Techniques in Phytochemotaxonomy
Felix Ifeanyi Nwafor and Ifeoma Celestina Orabueze

11. Chromatographical Techniques in Phytochemical Research
Sumera Javad and Shagufta Naz

12. UV/Visible Spectroscopy and HPLC in Phytochemical Analysis: An Introduction
Ade Kujore

13. HPLC and HPTLC as Sophisticated Tools in Phytochemical Analysis
Deepa R. Verma and Rohan V. Gavankar

14. Analytical Techniques in Elemental Profiling
Andrew G. Mtewa and Annu Amanjot

15. Phytochemical Test Methods
Chukwuebuka Egbuna, Jonathan C. Ifemeje, Maryann Chinenye Maduako, Tijjani Habibu, Stanley Chidi Udedi, Andrew C. Nwaka, and Maryjane Oluoma Ifemeje

16. Animal Models in Phytopharmacology
Ahmed A. Adedeji, Mulkah O. Ajagun-Ogunleye, and Marta Vicente-Crespo

17. Toxicological Testing of Plant Products
Monica Neagu and Carolina Constantin

18. Role of Biostatistics in Phytochemical Research: Emphasis on Essential Oil Studies
S. Zafar Haider, Gaurav Naik, Hema Lohani, and Nirpendra K. Chauhan

PART III: COMPUTATIONAL PHYTOCHEMISTRY
19. Computational Phytochemistry in Drug Discovery: Databases and Tools
Sugumari Vallinayagam, Karthikeyan Rajendran, and Vigneshkumar Sekar

20. Stemness Modulation by Phytochemicals to Target Cancer Stem Cells
Prem Prakash Kushwaha, Pushpendra Singh, and Shashank Kumar

21. Targeting Cancer Cell Carbohydrate Metabolism by Phytochemicals
Swastika Dash, Prem Prakash Kushwaha, and Shashank Kumar

22. Herbal Drug Discovery: The Envision Biotechnology Approach
A. Nagy

PART IV: PHYTOCHEMICAL RESEARCH
23. GC-MS Analysis and In Vitro Anticancer Activity of Tectona grandis Bark Extract Against Human Breast Cancer Cell Line (MCF-7)
R. Arul Priya, K. Saravanan, and B. Umarani

24. Phytochemical Analysis of Nigella sativa L. Seeds Aqueous Extract by GC-MS and FTIR
N. Shaista Jabeen, L. Jagapriya, B. Senthilkumar, K. Devi, and Jaison Jeevanandam

25. Phytochemical Studies on Five Nigerian Indigenous Vegetables
O. I. Faleyimu, T. Solomon, and A. J. Adebayo.


Index


About the Authors / Editors:
Editors: Chukwuebuka Egbuna
Research Biochemist, Department of Biochemistry, Faculty of Natural Sciences, Chukwuemeka Odumegwu Ojukwu University, Nigeria

Chukwuebuka Egbuna is a chartered chemist, a chemical analyst, and an academic researcher. He is a member of the Institute of Chartered Chemists of Nigeria (ICCON), the Nigerian Society of Biochemistry and Molecular Biology (NSBMB), and the Society of Quality Assurance (SQA) (USA). He has been engaged in a number of roles at New Divine Favor Pharmaceutical Industry Limited, Akuzor Nkpor, Anambra State, Nigeria, and Chukwuemeka Odumegwu Ojukwu University (COOU), Nigeria. He has collaboratively worked and published quite a number of research articles in the area of phytochemistry and its applications. He is a reviewer and editorial board member of various journals, with his most recent role as a website administrator for the Tropical Journal of Applied Natural Sciences (TJANS), a journal of the faculty of Natural Sciences, COOU. His primary research interests are in phytochemistry, food and medicinal chemistry, analytical chemistry, and nutrition and toxicology. He obtained his BSc and MSc degrees in biochemistry at Chukwuemeka Odumegwu Ojukwu University.

Jonathan Chinenye Ifemeje, PhD
Senior Lecturer, Department of Biochemistry, Faculty of Natural Sciences, Chukwuemeka Odumegwu Ojukwu University, Nigeria

Jonathan Chinenye Ifemeje, PhD, is a Senior Lecturer in the Department of Biochemistry, Faculty of Natural Sciences, Chukwuemeka Odumegwu Ojukwu University, Nigeria. He has to his credits over 40 publications and has served as an external examiner for various institutions. He is the Managing Editor of the Tropical Journal of Applied Natural Sciences and is currently serving as a reviewer and an editorial board member for various journals. He has worked extensively in the area of phytochemistry, nutrition, and toxicology. He is a member of various institutes, including the Institute of Chartered Chemists of Nigeria (ICCON), the Nigerian Society of Biochemistry and Molecular Biology (NSBMB), and Society of Quality Assurance (SQA). He obtained his PhD in applied biochemistry from Nnamdi Azikiwe University, Awka, Nigeria, and his MSc degree in nutrition and toxicology from the University of Port-Harcourt, Nigeria.

Stanley Chidi Udedi, PhD
Full Professor of Biochemistry, Department of Applied Biochemistry, Nnamdi Azikiwe University, (UNIZIK), Awka, Nigeria

Stanley Udedi Chidi, PhD, is a Full Professor of Biochemistry at the Department of Applied Biochemistry, Nnamdi Azikiwe University, (UNIZIK), Awka, Nigeria. He has taught in various institutions, including Madonna University Okija, Nigeria, and Anambra State University, which is now Chukwuemeka Odumegwu Ojukwu University, Nigeria. He is currently the Dean of Student Affairs at UNIZIK. He has worked extensively in the field of phytochemistry and food and medicinal chemistry and has supervised many MSc and PhD students. He is well published with over 50 publications, which has attracted over 170 citations. He is well traveled and has attended a series of workshops and conferences locally and internationally. He is a member of various professional institutes, which includes the Institute of Chartered Chemists of Nigeria (ICCON), the Nigerian Society of Biochemistry and Molecular Biology (NSBMB), the Nutrition Society of Nigeria, and others. He obtained his PhD and MSc degrees from UNIZIK, Nigeria.

Shashank Kumar, PhD
Assistant Professor, Center for Biochemistry and Microbial Sciences, Central University of Punjab, Bathinda, India

Shashank Kumar, PhD, is working as Assistant Professor at the Center for Biochemistry and Microbial Sciences, Central University of Punjab, Bathinda, India. He obtained his BSc, MSc, and PhD degrees in biochemistry from the Department of Biochemistry, University of Allahabad, Allahabad, India. He has worked as a Postdoctoral Fellow at the Department of Biochemistry, King George’s Medical University, Lucknow, India. Dr. Kumar has about 60 published scientific papers, reviews, editorial articles, and book chapters in various national and international peer-reviewed journals and has been cited more than 1,200 times. He has edited several books including Concepts in Cell Signaling and Carbohydrate Metabolism: Theory and Practical Approach, among others. He has expertise in the areas of free radical biology, cancer biology, characterization of plant products, xenobiotic metabolism, and microbiology. He is familiar with many biochemical techniques such as spectrophotometry, ELISA, electrophoresis, PCR, RT-PCR, flow cytometry, TLC, HPLC, LC-MS, cell culture, and microbiological techniques. He has presented his research findings at more than 25 national and international conferences and has attended about 30 workshops at many major universities and medical colleges throughout the India. Dr. Kumar is a life-time member of the Italo-Latin American Society of Ethnomedicine, and the Indian Sciences Congress Association, India, and a member of the Asian Council of Science Editors, Dubai, UAE and Publication Integrity & Ethics, London. He has been awarded junior, senior, and research associate fellowships formulated and funded by various Indian agencies, such as the Indian Council of Medical Research, University Grants Commission, and the Council of Scientific and Industrial Research India. Dr. Kumar’s laboratory has been funded by the University Grant Commission, India, and the Department of Science and Technology, India, for working on the effect of various phytochemicals on cancer cell signaling pathway inhibition.




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