Plant Science & Botany

Phytochemistry, 3-Volume Set
Volume 1: Fundamentals, Modern Techniques, and Applications
Volume 2: Pharmacognosy, Nanomedicine, and Contemporary Issues
Volume 3: Marine Sources, Industrial Applications, and Recent Advances


Editors: Chukwuebuka Egbuna
Jonathan Chinenye Ifemeje, PhD
Shashank Kumar, PhD
Stanley Chidi Udedi, PhD
Jaya Vikas Kurhekar, PhD
Nadia Sharif, PhD

Phytochemistry, 3-Volume Set

Published. Available now.
Pub Date: December 2018
Hardback Price: see ordering info
Hard ISBN: 9781771887625
Paperback Price: see ordering info
Paperback ISBN: 978-1-77463-523-0
E-Book Price:  9780429426278
E-Book ISBN: 9780429426155
Pages: 1806pp w/index
Binding Type: hardback / paperback / ebook
Notes: 43 color and 239 b/w illustrations

NOW AVAILABLE IN PAPERBACK

The 3-volume set, Phytochemistry, covers a wide selection of topics in phytochemistry and provides a wealth of information on the fundamentals, new applications, methods and modern analytical techniques, state-of-the-art approaches, and computational techniques. With chapters from professional specialists from around the world, the volumes deliver a comprehensive coverage of phytochemistry.

Volume 1: Fundamentals, Modern Techniques, and Applications begins with an introduction to phytochemistry and details the fundamentals. It then goes on to discuss the state-of-the-art modern methods and techniques in phytochemical research. It also provides an informative overview of computational phytochemistry and its applications and presents novel research findings in the discovery of drugs that will be effective in the treatment of diseases.

Volume 2: Pharmacognosy, Nanomedicine, and Contemporary Issues reviews a selection of important recent advances in ethnopharmacology and alternative and complementary medicines. It also presents chapters on the medicinal potential of phytochemicals in the treatment and management of various diseases, such as cancer, diabetes, diabetic nephropathy, autoimmune diseases, neurological disorders, male infertility, etc. The book also presents chapters that discuss recent developments in the green biosynthesis of metallic nanoparticles and nanoparticles of carbon dots and the biomedical applications and also looks at the toxic effects of phytochemicals as well as the prooxidant and antinutrient features.

Volume 3: Marine Sources, Industrial Applications, and Recent Advances discusses the industrial applications of phytochemicals, such as the production of secondary metabolites and accumulations through in vitro cultures. The volume reviews the effects of using natural products as biopesticides and as eco-friendly corrosion inhibitors. The book also discusses the effects of the environment on the distribution of phytochemicals and the roles of phytochelatins and heavy metal tolerance in plants.

Phytochemistry is a multidisciplinary field, so this book will appeal to upper-level students, faculty, researchers, and industry professionals in a number of fields, including biological science, biochemistry, pharmacy, food and medicinal chemistry, systematic botany and taxonomy, ethnobotany, conservation biology, plant genetic and metabolomics, evolutionary sciences, and plant pathology.

Key features:

  • Introduces phytochemistry, its modern history, and the relationship it has with other sciences
  • Discusses the prospects for phytochemists and the future of phytochemical research
  • Explores the biosynthesis of phytochemicals
  • Looks at the biological roles of phytochemicals
  • Details the role of phytochemistry in plant classification and various phytochemical markers of taxonomic importance
  • Describes the various extraction methods and techniques, including those for used for the isolation and characterization of phytochemicals
  • Discusses the role of phytochemicals in herbal medicines
  • Details the role of phytochemicals in the treatment and management of various diseases
  • Explores the green biosynthesis of nanoparticles and its biomedical applications
  • Reviews toxic plants and the ability of phytochemicals to act as prooxidants and antinutrients
  • Provides an overview of the techniques utilized in phytochemotaxonomy
  • Presents phytochemical biopesticides, an eco-friendly measure for pests

CONTENTS:
Phytochemistry, Volume 1: Fundamentals, Modern Techniques, and Applications

Preface

PART I: FUNDAMENTALS OF PHYTOCHEMISTRY
1. Introduction to Phytochemistry
Chukwuebuka Egbuna, Jonathan C. Ifemeje, Toskë L. Kryeziu, Minakshi Mukherjee, Hameed Shah, G.M. Narasimha Rao, Laurence John Francis J. Gido, and Tijjani Habibu

2. Biosynthesis of Phytochemicals
Tijjani Habibu, Chukwuebuka Egbuna, and Luka D. Carrol


3. Mechanisms of Plant Defense Against Pathogens: Phytoalexins Induction
Hanan M. AL-Yousef and Musarat Amina

4. Biological Roles of Phytochemicals
Onyekere Peculiar Feenna, Nwankwo Chioma Obianuju, Udodeme Helen Ogechukwu, Nnamani Daniel Okwudili, and Ezugwu Christopher Obodike

5. Phytochemicals as Immunomodulators
Behnaz Aslanipour

6. Phytochemicals as Nutraceuticals and Pharmafoods
Anywar Godwin

7. The Role of Phytochemistry in Plant Classification: Phytochemotaxonomy
Felix Ifeanyi Nwafor and Ifeoma Celestina Orabueze

8. Plant Metabolomics
Sagar Satish Datir and Rakesh Mohan Jha

PART II: METHODS AND TECHNIQUES
9. Phytochemical Extraction, Isolation and Detection Techniques
Temitope Temitayo Banjo, Paul Akinniyi Akinduti, Temitope Oluwabunmi Banjo, and Vinesh Kumar


10. Techniques in Phytochemotaxonomy
Felix Ifeanyi Nwafor and Ifeoma Celestina Orabueze

11. Chromatographical Techniques in Phytochemical Research
Sumera Javad and Shagufta Naz

12. UV/Visible Spectroscopy and HPLC in Phytochemical Analysis: An Introduction
Ade Kujore

13. HPLC and HPTLC as Sophisticated Tools in Phytochemical Analysis
Deepa R. Verma and Rohan V. Gavankar

14. Analytical Techniques in Elemental Profiling
Andrew G. Mtewa and Annu Amanjot

15. Phytochemical Test Methods
Chukwuebuka Egbuna, Jonathan C. Ifemeje, Maryann Chinenye Maduako, Tijjani Habibu, Stanley Chidi Udedi, Andrew C. Nwaka, and Maryjane Oluoma Ifemeje

16. Animal Models in Phytopharmacology
Ahmed A. Adedeji, Mulkah O. Ajagun-Ogunleye, and Marta Vicente-Crespo

17. Toxicological Testing of Plant Products
Monica Neagu and Carolina Constantin

18. Role of Biostatistics in Phytochemical Research: Emphasis on Essential Oil Studies
S. Zafar Haider, Gaurav Naik, Hema Lohani, and Nirpendra K. Chauhan

PART III: COMPUTATIONAL PHYTOCHEMISTRY
19. Computational Phytochemistry in Drug Discovery: Databases and Tools
Sugumari Vallinayagam, Karthikeyan Rajendran, and Vigneshkumar Sekar

20. Stemness Modulation by Phytochemicals to Target Cancer Stem Cells
Prem Prakash Kushwaha, Pushpendra Singh, and Shashank Kumar

21. Targeting Cancer Cell Carbohydrate Metabolism by Phytochemicals
Swastika Dash, Prem Prakash Kushwaha, and Shashank Kumar

22. Herbal Drug Discovery: The Envision Biotechnology Approach
A. Nagy

PART IV: PHYTOCHEMICAL RESEARCH
23. GC-MS Analysis and In Vitro Anticancer Activity of Tectona grandis Bark Extract Against Human Breast Cancer Cell Line (MCF-7)
R. Arul Priya, K. Saravanan, and B. Umarani

24. Phytochemical Analysis of Nigella sativa L. Seeds Aqueous Extract by GC-MS and FTIR
N. Shaista Jabeen, L. Jagapriya, B. Senthilkumar, K. Devi, and Jaison Jeevanandam

25. Phytochemical Studies on Five Nigerian Indigenous Vegetables
O. I. Faleyimu, T. Solomon, and A. J. Adebayo.


Index

Phytochemistry, Volume 2: Pharmacognosy, Nanomedicine, and Contemporary Issues

Preface

PART I: ETHNOMEDICINE AND PHARMACOGNOSY
1. Pharmacognosy and Prehistoric Uses of Medicinal Plants
Chukwuebuka Egbuna, Nadia Sharif, and N. Shaista Jabeen

2. Complementary and Alternative Systems of Medicines
Vinesh Kumar and Yogita Sharma

3. Ethnobotanical Study of Indigenous Peoples’ Medicinal Plants
Felix Ifeanyi Nwafor and Stella I. Inya-Agha

4. Herbal Medicine: A Case Study of Nigerian Medicinal Plants
Temitope A. Oyedepo

5. Plant Species Utilized for Ethnoveterinary Practices in India
V. Lakshminarayana and G. M. Narasimha Rao

PART II: MEDICINAL POTENTIALS OF PHYTOCHEMICALS
6. Antioxidants and Phytochemicals
Chukwuebuka Egbuna

7. Roles of Phytochemicals in the Prevention and Treatment of Various Diseases
Intan Soraya Che Sulaiman, Shibani Sukhi, and Azham Mohamad

8. Phytochemicals as Oxidative Stress Mitigators
Ashutosh Gupta and Abhay K. Pandey

9. Antimicrobial Medicinal Plants as Effective Natural Bioresources
Jaya Vikas Kurhekar

10. Medicinal Plants with Anti-Venom Activities
Habibu Tijjani and Chukwuebuka Egbuna

11. Medicinal Potentials of Green Tea
Frederick O. Ujah

12. Antioxidant Potentials of Cinnamon
S. Zafar Haider, Hema Lohani, Dolli Chauhan, and Nirpendra K. Chauhan

13. Phytochemical as the Hope for the Treatment of Hepatic and Neuronal Disorders
Swagata Das, Prareeta Mahapatra, Priyanka Kumari, Prem Prakash Kushwaha, Pushpendra Singh, and Shashank Kumar

14. Role of Phytochemicals in the Treatment of Male Infertility
Vijaykumar K. Parmar and Ketan Variya

15. Roles of Medicinal Plants in the Treatment of Cancer
Prabhat Upadhyay, Rashmi Shukla, Sunil Kumar Mishra, Rinki Verma, Suresh Purohit, and G. P Dubey

16. Methylated Flavonoids as a Novel Inhibitor of Metastasis in the Cancer Cell
Prem Prakash Kushwaha, Pushpendra Singh, and Shashank Kumar

17. Medicinal Roles of Phytomolecules in the Treatment and Management of Diabetes Mellitus
Maria Aslam, Sidra Khalid, and Hafsa Kamran

18. Roles of Phytomolecules in the Treatment of Diabetic Nephropathy
Rashmi Shukla, Prabhat Upadhyay, and Yamini B. Tripathi

19. Phytochemicals as Protagonist for the Treatment and Management of Autoimmune Diseases
Pragya Mishra, Parjanya Kumar Shukla, and Raghvendra Raman Mishra

PART III: NANOPARTICLE BIOSYNTHESIS AND ITS BIOMEDICAL APPLICATIONS
20. Green Biosynthesis of Metallic Nanoparticles
Seshu Vardhan Pothabathula, Prem Prakash Kushwaha, and Shashank Kumar

21. Cytotoxicity and Biomedical Applications of Metal Oxide Nanoparticles Synthesized from Plants
Hii Yiik Siang, Jaison Jeevanandam, Chan Yen San, and Michael K. Danquah

22. Biosynthesis of Carbon Dot’s Nanoparticles from Plants
Hameed Shah and Ashfaq Ahmad Khan

PART IV: PHYTOCHEMICALS AS FRIENDS AND FOES
23. Toxic Plants and Phytochemicals
Chukwuebuka Egbuna, Alan Thomas S., Onyeka Kingsley Nwosu, Olumayowa Vincent Oriyomi, Toskë L. Kryeziu, Saravanan Kaliyaperumal, and Jonathan C. Ifemeje

24. Phytochemicals as Prooxidants
Andrew G. Mtewa

25. Phytochemical as an Antinutrient
Chukwuebuka Egbuna

Index

Phytochemistry, Volume 3: Marine Sources, Industrial Applications, and Recent Advances

Preface

PART I: MARINE SOURCES OF SECONDARY METABOLITES
1. Phytochemicals of Marine Origin
Nadia Sharif, Sana Nayab, Syeda Nazish Arshad, Neelma Munir, and Shagufta Naz

2. Marine Sponge Alkaloids: A Source of Novel Anticancer Agent
Musarat Amina and Hanan M. Al-Yousef

3. Marine Antioxidants and Assay Methods
Onyeka Kingsley Nwosu and David Okechukwu Okeke

4. Extraction of Marine Phytochemicals: Methods and Techniques
Nadia Sharif, Neelma Munir, and Shagufta Naz

PART II: INDUSTRIAL AND MEDICINAL APPLICATIONS OF PHYTOCHEMICALS
5. Biotechnology Approach to the Production of Phytochemicals: An Introduction
Hameed Shah, Andrew G. Mtewa, Chukwuebuka Egbuna, Anywar Godwin, and Duncan C. Sesaazi

6. Secondary Metabolites Accumulation and Production through In Vitro Cultures
Hussien M. Daffalla and Azza Migdam Elsheikh

7. Practical Processes Involved in the Production of Phytochemicals by Plant Tissue Culture
Hanan M. Al-Yousef

8. Medicinal and Industrial Applications of Bromelain
Ramesh Kumar and Abhay K. Pandey

9. Cysteine Proteases from Plants and Its Applications
Juan Abreu Payrol, Walter David Obregón, Juliana Cotabarren, T. B. Mutsauri, and Inidia Rubio Vargas

10. Phytotherapy and Encapsulation
?aban Keskin, Merve Keskin, and Sevgi Kolayl?

11. Effective Processing Methods for Fruits and Vegetables
Maria Aslam, Sidra Khalid, and Hafsa Kamran

PART III: ENVIRONMENTAL CONCERNS AND ECO-FRIENDLY CONTROL MEASURES
12. Effects of Environmental Factors on the Accumulation of Phytochemicals in Plants
Sechene Stanley Gololo

13. Effects of Environment on the Chemical Constituents and Biological Characteristics of Some Medicinal Plants
Vinesh Kumar and Yogita Sharma

14. Phytochelatins and Heavy Metal Tolerance in Plants
Maria Catherine B. Otero and Genevieve D. Tupas

15. Phytochemical Biopesticides
Olumayowa Vincent Oriyomi

16. Sustainable Approach in Integrated Pest Management: Role of Phytomolecules as Biopesticide
Rakesh Kumar Gupta, Prem Prakash Kushwaha, and Shashank Kumar

17. Essential Oil in Pest Control and Disease Management
Arvind Saroj, Atul Kumar Srivatava, Ashish Kumar Nayak, C. S. Chanotiya, and A. Samad

18. Inhibition of Mild Steel Corrosion in Acidic Media by Phytochemicals
Basu Maan Daas

PART IV: RECENT ADVANCES
19. Novel Terpenoids as Anticancer Stem Cell Agents
Rebati Malik, Santosh Kumar Maurya, Prem Prakash Kushwaha, Pushpendra Singh, and Shashank Kumar

20. Evaluation of the Phytohemagglutinin Activities of Echinacea Species in Ontogenesis
Sergey V. Pospelov

Index


About the Authors / Editors:
Editors: Chukwuebuka Egbuna
Research Biochemist, Department of Biochemistry, Faculty of Natural Sciences, Chukwuemeka Odumegwu Ojukwu University, Nigeria

Chukwuebuka Egbuna is a chartered chemist, a chemical analyst, and an academic researcher. He is a member of the Institute of Chartered Chemists of Nigeria (ICCON), the Nigerian Society of Biochemistry and Molecular Biology (NSBMB), and the Society of Quality Assurance (SQA) (USA). He has been engaged in a number of roles at New Divine Favor Pharmaceutical Industry Limited, Akuzor Nkpor, Anambra State, Nigeria, and Chukwuemeka Odumegwu Ojukwu University (COOU), Nigeria. He has collaboratively worked and published quite a number of research articles in the area of phytochemistry and its applications. He is a reviewer and editorial board member of various journals, with his most recent role as a website administrator for the Tropical Journal of Applied Natural Sciences (TJANS), a journal of the faculty of Natural Sciences, COOU. His primary research interests are in phytochemistry, food and medicinal chemistry, analytical chemistry, and nutrition and toxicology. He obtained his BSc and MSc degrees in biochemistry at Chukwuemeka Odumegwu Ojukwu University.

Jonathan Chinenye Ifemeje, PhD
Senior Lecturer, Department of Biochemistry, Faculty of Natural Sciences, Chukwuemeka Odumegwu Ojukwu University, Nigeria

Jonathan Chinenye Ifemeje, PhD, is a Senior Lecturer in the Department of Biochemistry, Faculty of Natural Sciences, Chukwuemeka Odumegwu Ojukwu University, Nigeria. He has to his credits over 40 publications and has served as an external examiner for various institutions. He is the Managing Editor of the Tropical Journal of Applied Natural Sciences and is currently serving as a reviewer and an editorial board member for various journals. He has worked extensively in the area of phytochemistry, nutrition, and toxicology. He is a member of various institutes, including the Institute of Chartered Chemists of Nigeria (ICCON), the Nigerian Society of Biochemistry and Molecular Biology (NSBMB), and Society of Quality Assurance (SQA). He obtained his PhD in applied biochemistry from Nnamdi Azikiwe University, Awka, Nigeria, and his MSc degree in nutrition and toxicology from the University of Port-Harcourt, Nigeria.

Shashank Kumar, PhD
Assistant Professor, Center for Biochemistry and Microbial Sciences, Central University of Punjab, Bathinda, India

Shashank Kumar, PhD, is working as Assistant Professor at the Center for Biochemistry and Microbial Sciences, Central University of Punjab, Bathinda, India. He obtained his BSc, MSc, and PhD degrees in biochemistry from the Department of Biochemistry, University of Allahabad, Allahabad, India. He has worked as a Postdoctoral Fellow at the Department of Biochemistry, King George’s Medical University, Lucknow, India. Dr. Kumar has about 60 published scientific papers, reviews, editorial articles, and book chapters in various national and international peer-reviewed journals and has been cited more than 1,200 times. He has edited several books including Concepts in Cell Signaling and Carbohydrate Metabolism: Theory and Practical Approach, among others. He has expertise in the areas of free radical biology, cancer biology, characterization of plant products, xenobiotic metabolism, and microbiology. He is familiar with many biochemical techniques such as spectrophotometry, ELISA, electrophoresis, PCR, RT-PCR, flow cytometry, TLC, HPLC, LC-MS, cell culture, and microbiological techniques. He has presented his research findings at more than 25 national and international conferences and has attended about 30 workshops at many major universities and medical colleges throughout the India. Dr. Kumar is a life-time member of the Italo-Latin American Society of Ethnomedicine, and the Indian Sciences Congress Association, India, and a member of the Asian Council of Science Editors, Dubai, UAE and Publication Integrity & Ethics, London. He has been awarded junior, senior, and research associate fellowships formulated and funded by various Indian agencies, such as the Indian Council of Medical Research, University Grants Commission, and the Council of Scientific and Industrial Research India. Dr. Kumar’s laboratory has been funded by the University Grant Commission, India, and the Department of Science and Technology, India, for working on the effect of various phytochemicals on cancer cell signaling pathway inhibition.

Stanley Chidi Udedi, PhD
Full Professor of Biochemistry, Department of Applied Biochemistry, Nnamdi Azikiwe University, (UNIZIK), Awka, Nigeria

Stanley Chidi Udedi , PhD, is a Full Professor of Biochemistry at the Department of Applied Biochemistry, Nnamdi Azikiwe University, (UNIZIK), Awka, Nigeria. He has taught in various institutions, including Madonna University Okija, Nigeria, and Anambra State University, which is now Chukwuemeka Odumegwu Ojukwu University, Nigeria. He is currently the Dean of Student Affairs at UNIZIK. He has worked extensively in the field of phytochemistry and food and medicinal chemistry and has supervised many MSc and PhD students. He is well published with over 50 publications, which has attracted over 170 citations. He is well traveled and has attended a series of workshops and conferences locally and internationally. He is a member of various professional institutes, which includes the Institute of Chartered Chemists of Nigeria (ICCON), the Nigerian Society of Biochemistry and Molecular Biology (NSBMB), the Nutrition Society of Nigeria, and others. He obtained his PhD and MSc degrees from UNIZIK, Nigeria.

Jaya Vikas Kurhekar, PhD
Associate Professor, Department of Microbiology, Dr. Patangrao Kadam Mahavidyalaya, Sangli, India

Jaya Vikas Kurhekar, PhD (microbiology), MBA (human resources), is presently the Head and Associate Professor in Microbiology, teaching undergraduate and postgraduate students, in the Department of Microbiology at the college Dr. Patangrao Kadam Mahavidyalaya, Sangli, India. She is a guide for MPhil and PhD (Microbiology) at Shivaji University, Kolhapur, Bharati Vidyapeeth University, Pune, and examiner for PhD candidates at Mumbai University, Mumbai, and Cairo University, Egypt. Her areas of research interest are phytochemistry, pharmacognosy, environmental microbiology, medical microbiology, and agricultural microbiology. She has published over 40 scientific papers in various international and national journals. She has also been a reviewer for many international and national journals and has worked as an editor for special journal issues in microbiology. She has been the editor and contributor to the textbooks on microbiology and has three of her books translated. She has presented many scientific papers at international and national conferences and has been invited as a speaker and chairperson at conferences. She has made significant contributions to the Encyclopedia of Scientists in Microbiology, being compiled and edited by the Maharashtra State Marathi Encyclopedia Creation Board, Mumbai, India. She has successfully undertaken five minor research projects funded by the University Grants Commission, New Delhi, India, and has attended over 100 international and national research gatherings. Dr. Kurhekar is a life member of various associations, including the Indian Association of Medical Microbiology; Indian Society of Pharmacognosy; Association of Microbiologists of India, Sangli Unit; Society of Environmental Sciences; Microbiologists Society; Society for Current Sciences; and Swamy Botanical Club.

Nadia Sharif, PhD
Lecturer, Biotechnology Department of Lahore, College for Women, University, Lahore, Pakistan

Nadia Sharif, PhD, is currently working as a Visiting Lecturer at the Biotechnology Department of Lahore College for Women, University, Lahore, Pakistan. She has published over 20 scientific papers, reviews, and book chapters in various books and national and international peer-reviewed journals. Dr. Sharif is serving as a reviewer for the British Microbiology Research Journal, African Journal of Microbiology Research, and Natural Product Journal, and she has presented her research findings at national conferences. She has expertise in areas of phycology, industrial biotechnology, microbiology, molecular biology biostatistics, and biochemistry. She is familiar with many biochemical techniques such as spectrophotometry, electrophoresis, PCR, ASE, TLC, HPLC, GC-MS, cell culture, and microbiological techniques. She has a great interest in working for the sustainable use of natural resources. She obtained her MSc degree in Zoology from Bahauddin Zakariya University, Multan, Pakistan, and did her PhD in the Biotechnology Department of Lahore College for Women University, Lahore, Pakistan. She was awarded an Indigenous and International Fellowship (IRSIP) by the Higher Education Commission, Pakistan. She visited the Chemical and Biochemical Engineering Department of Johns Hopkins University, Baltimore, Maryland, USA, for her PhD research.




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