Chemistry

Handbook of Research on Medicinal Chemistry
Innovations and Methodologies

Editors: Debarshi Kar Mahapatra, PhD
Sanjay Kumar Bharti, PhD

Handbook of Research on Medicinal Chemistry

Now on press
Pub Date: November 2017
Hardback Price: $229.95 US
Hard ISBN: 9781771885447
E-Book ISBN: 9781315207414
Pages: 648pp w/ Index
Binding Type: hardback
Notes: 5 color and 87 b/w illustrations

This valuable new book, Handbook of Research on Medicinal Chemistry: Innovations and Methodologies, presents some of the latest advancements in the various fields of combinatorial chemistry, drug discovery, biochemical aspects, pharmacology of medicinal agents, current practical problems, and nutraceuticals.

The editors keep the drug molecule as the central component of the volume and aim to explain the associated features essential to exhibiting pharmacological activity. With a unique combination of chapters in biology, clinical aspects, biochemistry, synthetic chemistry, medicine and technology, the volume provides broad exposure to the essential aspect of pharmaceuticals.
The volume many important aspects of medicinal chemistry, including

  • techniques in drug discovery
  • pharmacological aspects of natural products
  • chemical mediators: druggable targets
  • advances in medicinal chemistry
The field of medicinal chemistry is growing at an unprecedented pace, and this volume takes an interdisciplinary approach, covering a range of new research and new practices in the field. The volume takes into account the latest therapeutic guidelines put forward by the World Health Organization and the U.S Food and Drug Administration..

Topics include:
  • drug design
  • drug discovery
  • natural products and supplements and nutraceuticals
  • pharmaceutical approaches to sexual dysfunction
  • drug resistance parasites
  • new natural compounds and identification of new targets
  • stereochemistry aspects in medicinal chemistry
  • common drug interactions in daily practices
Handbook of Research on Medicinal Chemistry: Innovations and Methodologies will be a valuable addition to the bookshelves of pharmaceutical scientists and faculty as well as for industry professionals.

CONTENTS:
Preface
PART I: TECHNIQUES IN DRUG DISCOVERY
1. Combinatorial Chemistry: Role in Lead Discovery
Premlata K. Ambre, Anish N. Gomatam, Santosh Nandan, and Evans C. Coutinho
2. Advanced Techniques in Bimolecular Simulations
Anirudh V. Belubbi and Elvis A. F. Martis
3. Retrometabolic Drug Design
Nirzari Gupta

PART II: PHARMACOLOGICAL ASPECTS OF NATURAL PRODUCTS
4. Insight Into The Pharmacological Potentials of Camellia sinensis Linn.
Prabodh Chander Sharma, Amit Yadav, Archana Sharma, and Aakash Deep
5. Pharmaceutical Importance of Natural Aphrodisiac Drugs
Ram Kumar Sahu and Amit Roy

PART III: CHEMICAL MEDIATORS: DRUGGABLE TARGETS
6. Serotonin: Chemical, Biological and Therapeutic Aspects
Bibhudatta Mishra and Gunjan Joshi
7. Eicosanoids: Constitution and Pathophysiological Functions
Gunjan Joshi

PART IV: ADVANCES IN MEDICINAL CHEMISTRY
8. Development of Antimalarial Drug Analogues to Combat Plasmodium Resistance
Shivani Sharma, Aakash Deep, Manav Malhotra, and Balasubramanian Narasimhan
9. Chemistry and Pharmacology of Β-Lactam Analogues
Ankur Vaidya and Shweta Jain
10. General Anaesthetics
T. N. V. Ganesh Kumar
11. Stereochemical Aspects in Medicinal Chemistry
Sidhartha S. Kar
12. Pharmaceutical Interactions in Drug Practices
Sachinkumar Patil, Shitalkumar Patil, Sudha Kharade, and Dipali Kamble

Index


About the Authors / Editors:
Editors: Debarshi Kar Mahapatra, PhD
Assistant Professor, Department of Pharmaceutical Chemistry, Dadasaheb Balpande College of Pharmacy, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, Maharashtra, India

Debarshi Kar Mahapatra, PhD, is currently Assistant Professor, Department of Pharmaceutical Chemistry, Dadasaheb Balpande College of Pharmacy, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, Maharashtra, India. He was formerly Assistant Professor in the Department of Pharmaceutical Chemistry, Kamla Nehru College of Pharmacy, RTM Nagpur University, Nagpur, India. He taught medicinal and computational chemistry at both the undergraduate and postgraduate levels and has mentored students in their various research projects. His area of interest includes computer-assisted rational designing and synthesis of low molecular weight ligands against druggable targets, drug delivery systems, and optimization of unconventional formulations. He has published research, book chapters, reviews, and case studies in various reputed journals and has presented his work at several international platforms, for which he received several awards by a number of bodies. He has also authored the book titled Drug Design. Presently, he is serving as reviewer and editorial board member for several journals of international repute. He is a member of a number of professional and scientific societies, such as the International Society for Infectious Diseases (ISID), the International Science Congress Association (ISCA), and ISEI.

Sanjay Kumar Bharti, PhD
Assistant Professor, Institute of Pharmaceutical Sciences, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur, India

Sanjay Kumar Bharti, PhD, is an Assistant Professor in Institute of Pharmaceutical Sciences, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur. He has working experience in several organizations, such as Win-Medicare Pvt. Ltd, Meerut, India (as a chemist) and the National Institute of Pharmaceutical Education and Research (NIPER), Hajipur (as a lecturer). He has published several research papers, one book, several book chapters and review articles in various reputed journals. His research interest includes synthesis of Schiff’s base, heterocyclic compounds, and metallopharmaceuticals for therapeutics. He is an active member of various scientific and pharmaceutical organizations like IPA, IPGA, ISCA, etc. Dr. Bharti has completed a BPharm from IT-BHU, Varanasi, India, in 2003, an M.Pharm from RGPV, Bhopal, India, in 2004, and a PhD from IIT-BHU, Varanasi, India, in 2011.




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