Medicine & Health Sciences

Clinical Nutrition and Aging
Sarcopenia and Muscle Metabolism

Chad Cox, PhD

Clinical Nutrition and Aging

Published. Available now.
Pub Date: March 2016
Hardback Price: $149.95 US
Hard ISBN: 9781771883702
E-Book ISBN: 9781771883719
Pages: 306 pp with index
Binding Type: hardback

This title includes a number of Open Access chapters.

Sarcopenia—the loss of muscle mass and strength that occurs with advancing age—is a major health challenge, particularly in North America, Europe, and Japan, which have large aging populations. This compendium volume is a valuable addition to the existing literature, providing state-of-the-art information on the most effective prevention and treatment options.

Included are research articles on:
  • nutrition management and the prevention of sarcopenia
  • protein therapy for sarcopenia
  • the effect of exercise on sarcopenia
  • other therapeutic strategies, including antioxidants and steroids
Written by experts in the field from the US, Canada, Italy, the UK, Belgium, Chile, France, and Japan, this book will be of practical international interest to geriatricians, nutritionists, and dietitians, as well as clinicians and professionals working in nursing homes or sports medicine. It is also a valuable reference for postgraduates and researchers working on age-related diseases, disability, nutrition, and geriatric medicine.

Part I: How Nutrition and Other Factors Relate to Sarcopenia
1. Nutrition and Sarcopenia: A Review of the Evidence and Implications for Preventive Strategies
Siân Robinson, Cyrus Cooper, and Avan Aihie Sayer
2. Malnutrition-Sarcopenia Syndrome: Is This the Future of Nutrition Screening and Assessment for Older Adults?
Maurits F. J. Vandewoude, Carolyn J. Alish, Abby C. Sauer, and Refaat A. Hegazi
3. Novel Insights on Nutrient Management of Sarcopenia in the Elderly
Mariangela Rondanelli, Milena Faliva, Francesca Monteferrario, Gabriella Peroni, Erica Repaci, Francesca Allieri, and Simone Perna

Part II: Protein and Exercise
4. Whey Protein and Essential Amino Acids Promote the Reduction of Adipose Tissue and Increased Muscle Protein Synthesis During Caloric Restriction-Induced Weight Loss in Elderly, Obese Individuals
Robert H. Coker, Sharon Miller, Scott Schutzler, Nicolaas Deutz, and Robert R. Wolfe
5. Insulinotropic and Muscle Protein Synthetic Effects of Branched-Chain Amino Acids: Potential Therapy for Type 2 Diabetes and Sarcopenia
Ralph J. Manders, Jonathan P. Little, Scott C. Forbes, and Darren G. Candow
6. Myofibrillar Protein Synthesis Following Ingestion of Soy Protein Isolate at Rest and After Resistance Exercise in Elderly Men
Yifan Yang, Tyler A. Churchward-Venne, Nicholas A. Burd, Leigh Breen, Mark A. Tarnopolsky, and Stuart M. Phillips
7. The Link between Dietary Protein Intake, Skeletal Muscle Function and Health in Older Adults
Jamie I. Baum and Robert R. Wolfe
8. The Pleiotropic Effect of Physical Exercise on Mitochondrial Dynamics in Aging Skeletal Muscle
Elena Barbieri, Deborah Agostini, Emanuela Polidori, Lucia Potenza, Michele Guescini, Francesco Lucertini, Giosuè Annibalini, Laura Stocchi, Mauro De Santi, and Vilberto Stocchi

Part III: Other Therapeutic Strategies
9. Novel Intriguing Strategies Attenuating to Sarcopenia 215
Kunihiro Sakuma and Akihiko Yamaguchi
10. Muscle Wasting and Resistance of Muscle Anabolism: The “Anabolic Threshold Concept” for Adapted Nutritional Strategies during Sarcopenia
Dominique Dardevet, Didier Rémond, Marie-Agnès Peyron, Isabelle Papet, Isabelle Savary-Auzeloux, and Laurent Mosoni
11. Rationale for Antioxidant Supplementation in Sarcopenia
Francesco Cerullo, Giovanni Gambassi, and Matteo Cesari
12. Sarcopenia and Androgens: A Link between Pathology and Treatment
Carla Basualto-Alarcón, Diego Varela, Javier Duran, Rodrigo Maass, and Manuel Estrada

About the Authors / Editors:

Chad Cox, PhD
Lecturer, Department of Chemistry and Department of Family and Consumer Sciences, California State University, Sacramento, California, USA

Dr. Chad L. Cox is a lecturer in the Department of Chemistry and the Department of Family and Consumer Sciences at California State University, Sacramento. He also teaches at Sacramento City College and the University of California, Davis. He holds a PhD in Nutritional Biology, a Bachelor of Science in Exercise Biology, and a Bachelor of Science in Nutrition Science, all from UC Davis. His research interests include the causes of obesity and obesity-related chronic diseases, how exercise training can induce changes in the regulation of gene expression that can lead to improvements in insulin sensitivity and promote energy balance, and the development of pharmacological agents that could help reduce the epidemic of obesity, Type 2 diabetes and metabolic syndrome.

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