Biotechnology and Bioinformatics
Advances and Applications for Bioenergy, Bioremediation and Biopharmaceutical Research

Editors: Devarajan Thangadurai, PhD
Jeyabalan Sangeetha, PhD

Biotechnology and Bioinformatics

Published. Available now.
Pub Date: July 2014
Hardback Price: $189.95 US
Hard ISBN: 9781771880015
Pages: 524 pages with index
Binding Type: hardbound

Here is an important source for the advanced technologies of modern biotechnology. It encompasses with a wide range of topics. It highlights the roles of targeted delivery of polymeric nanodrugs to cancer cells and microbial detoxifying enzymes in bioremediation and bacterial plasmids in antimicrobial resistance, while also addressing modern trends such as pharmacogenomics, gene expression, recombinant proteins from methylotrophic yeast, novel fermentation inhibitors of bioethanol production, and polyhydroxyalkanoate-based biomaterials. The book also covers the practical utility of biotechnology and bioinformatics for bioenergy, environmental remediation, production of high value biochemicals, modeling molecular interactions, drug discovery, and healthcare and personalized medicine.

Modern biotechnology is an interdisciplinary, revolutionary, and beneficial branch of biology that encompasses various advanced techniques. In agriculture, biotechnology plays a crucial role for crop improvement to transfer genes between different plants to enhance characteristics such as yield and disease resistance. In healthcare, the role of biotechnology encompasses genetic testing, gene therapy, drug development, and pharmacogenomics. Bioengineering is the physical side of biotechnology that focuses on the genetic manipulation in the biological systems. In the current scenario, bioremediation and biodegradation play a crucial role by focusing on the design and development of technologies using microorganisms to cleanup environmental pollution. Application of biotechnological aspects with the knowledge of bioinformatics further leads to the development of newer technologies. In order to apply the knowledge of biotechnology, we need the support of bioinformatics to acquire relevant information of biological data. In the era of molecular medicine and personalized genomics, there needs to be an integration of genomic, cellular, molecular, and clinical data which are all possible through bioinformatics.

The book is aimed at graduates, scholars, biotechnology researchers, and bioinformatics professionals in applied biotechnology, bioengineering, biomedical sciences, microbiology and environmental sciences to broaden their knowledge about these newer tools, techniques, innovations, and applications.

Chapter 1: Polymeric Nanoparticle Mediated Targeted Drug Delivery to Cancer Cells
Gul-E-Saba and Mohd Azmuddin Abdullah (Malaysia)

Chapter 2: Pharmacogenetics and Pharmacogenomics in Personalized Medicine: Role of Gene Polymorphism in Drug Response

Rownock Afruza, Fumiaki Suzuki, and A. H. M. Nurun Nabi (Bangladesh, Japan)

Chapter 3: Natural History and Molecular Biology of Hepatitis B Virus

Essam Mohammed Janahi (Kingdom of Bahrain)

Chapter 4: Reconfigurable Parallel Platforms for Dependable Personalized Health Monitoring

Olufemi Adeluyi and Jeong A. Lee (Republic of South Korea)

Chapter 5: High Throughput Evaluation of Gene Expression from Formalin-Fixed Paraffin-Embedded Tissues

Paraskevi A. Farazi (Cyprus)

Chapter 6: Microbial Detoxifying Enzymes Involved in Biodegradation of Organic Chemopollutants

Pradnya Pralhad Kanekar and Seema Shreepad Sarnaik (India)

Chapter 7: An Insight Into Horizontal Gene Transfer Triggering Widespread Antimicrobial Resistance in Bacteria

Zakir Hossain (Bangladesh)

Chapter 8: Production and Biotechnological Applications of Recombinant Proteins by Methylotrophic Yeast: Past, Present and Future Perspectives

Marcos López-Pérez and Rina María González-Cervantes (Mexico)

Chapter 9: Mechanism of Tolerance and Engineering of Yeast Strain Resistant to Novel Fermentation Inhibitors of Bioethanol Production

Lahiru Niroshan Jayakody, Nobuyuki Hayashi, and Hiroshi Kitagaki (Japan)

Chapter 10: Biotechnological Potential of Alkaliphilic Microorganisms

Pradnya Pralhad Kanekar, Amaraja Abhay Joshi, Snehal Omkar Kulkarni, Suchitra Baburao Borgave, Seema Shreepad Sarnaik, Smita Shrikant Nilegaonkar, Anita Satish Kelkar, and Rebecca Sandeep Thombre (India)

Chapter 11: Design and Tailoring of Polyhydroxyalkanoate-Based Biomaterials Containing 4-Hydroxybutyrate Monomer

Sevakumaran Vigneswari, Kesaven Bhubalan, and Abdullah Al-Ashraf Amirul (Malaysia)

Chapter 12: Algal Biotechnology for Bioenergy, Environmental Remediation and High-Value Biochemicals

Mohd Azmuddin Abdullah, Syed Muhammad Usman Shah, Ashfaq Ahmad, and Hamdy El-Sayed (Malaysia)

Chapter 13: Molecular Docking: A Practical Approach for Protein Interaction Analysis

Neil Andrew D. Bascos (Philippines)

Chapter 14: Application of Biotechnology and Bioinformatics in Drug Designing and Discovery

A. K. M. Mahbub Hasan, Sajib Chakrobarty, Rajib Chakrovorty, and A. H. M. Nurun Nabi (Australia, Bangladesh)

Chapter 15: Systems Biotechnology for Industrial Microorganisms

Ana M. Martins (United Arab Emirates)

Chapter 16: Bioinformatics and Biotechnology in Human Genetic Research: A Current Scenario

Sathiya Maran, Thirumulu Ponnuraj Kannan, and Teguh Haryo Sasongko (Malaysia)


About the Authors / Editors:
Editors: Devarajan Thangadurai, PhD
Senior Assistant Professor, Karnatak University, Dharwad, India

Devarajan Thangadurai, PhD, is Senior Assistant Professor at Karnatak University in South India. He is also President of the Society for Applied Biotechnology; General Secretary of the Association for the Advancement of Biodiversity Science; and Journal Editor-in-Chief of several journals: Biotechnology, Bioinformatics and Bioengineering; Acta Biologica Indica; Biodiversity Research International; and Asian Journal of Microbiology. He received his PhD in botany from Sri Krishnadevaraya University in South India (2003). During 2002-2004, he worked as CSIR Senior Research Fellow with funding from the Ministry of Science and Technology, Government of India. He served as a postdoctoral fellow at the University of Madeira (Portugal), University of Delhi (India), and ICAR National Research Centre for Banana (India) from 2004 to 2006. He is the recipient of Best Young Scientist Award with Gold Medal from Acharya Nagarjuna University (2003) and the VGST-SMYSR Young Scientist Award of Government of Karnataka, Republic of India (2011). He has edited or authored 15 books, including Genetic Resources and Biotechnology (3 vols.), Genes, Genomes and Genomics (2 vols.) and Mycorrhizal Biotechnology, with publishers of national and international reputation.

Jeyabalan Sangeetha, PhD
UGC Kothari Postdoctoral Fellow at Karnatak University, Dharwad, India

Jeyabalan Sangeetha, PhD, earned his BSc in microbiology (2001) and PhD in environmental sciences (2010) from Bharathidasan University, Tiruchirappalli, Tamil Nadu, India. She holds also an MSc in environmental sciences (2003) from Bharathiar University, Coimbatore, Tamil Nadu, India. Between 2004 and 2008, she was the recipient of Tamil Nadu Government Scholarship and the Rajiv Gandhi National Fellowship of University Grants Commission, Government of India for her doctoral studies. She has published approximately 20 manuscripts detailing the effect of pollutants on the environment, and she has organized conferences, seminars, workshops, and lectures. Her main research interests are in the areas of environmental microbiology and environmental biotechnology, with particular emphasis on solid waste management, environmental impact assessment and microbial degradation of hydrocarbons. Her scientific and community leadership have included serving as an editor of the journal of Biodiversity Research International, and acting as Secretary of the Society for Applied Biotechnology. Presently, she is the UGC Kothari Postdoctoral Fellow at Karnatak University in South India.

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